Abstract #1264

Aerobic exercise enhances 31P MRS measured mitochondrial function independent of statin use

Jill M Slade¹, George S Abela², David M Hurley¹, and Ronald A Meyer³

¹Radiology, Michigan State University, East Lansing, MI, United States, ²Medicine, Michigan State University, East Lansing, MI, United States, ³Physiology, Michigan State University, East Lansing, MI, United States

Phosphorus MRS is the gold standard measure of in vivo mitochondrial function. In this study, ³¹P MRS was used to examine exercise-induced adaptations in mitochondrial function in the presence of concurrent statin use. The results show that aerobic exercise training significantly improved muscle oxidative capacity of the plantar flexor muscles in older adults independent of statin use.

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