Abstract #1265

The novel visualization technique of fast and slow muscle fibers using q-space imaging: Clinical study

Daisuke Nakashima¹, Junichi Hata^2,3,4, Yasushi Sera⁵, Takeo Nagura⁶, Morio Matsumoto¹, Hideyuki Okano⁴, and Masaya Nakamura¹

¹Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan, ²RIKEN Brain Science Institute, Saitama, Japan, ³Central Institute for Experimental Animals, Kanagawa, Japan, ⁴Department of Physiology, Keio University School of Medicine, Tokyo, Japan, ⁵Institute for Integrated Sports Medicine, Keio University School of Medicine, Tokyo, Japan, ⁶Department of Clinical Biomechanics, Keio University School of Medicine, Tokyo, Japan

Skeletal muscles include fast and slow muscle fibers. However, a non-invasive approach for appropriately investigating the characteristics of muscles is not available. The present study aimed to determine whether q-space imaging can distinguish between fast fiber dominant tibialis anterior muscle (TA) and slow fiber dominant soleus muscle (SOL). T2WI, FA and ADC maps could not represent the difference between TA and SOL. On the other hand, Kurtosis map could visualize the characteristics of TA and SOL. q-space imaging is a promising method to non-invasively estimate the fiber type ratio in skeletal muscles.

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