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Abstract #1273

The relation between fat calibration in multi-echo spin-echo water T2 mapping and STEAM fat T2 relaxation measurements

Martijn Froeling1, Eric Hughes2, Lara Schlaffke3, Hermien E Kan4, and Kieren G Hollingsworth2

1Department of Radiology, University medical center utrecht, Utrecht, Netherlands, 2Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom, 3Department of Neurology BG, University Hospital Bergmannsheil, Ruhr-University Bochum, Bochum, Germany, 4Dept of Radiology, C.J. Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, Netherlands

The aim of this study was to quantitatively describe the relation between fat calibration in ME-SE water T2 mapping and STEAM fat T2 relaxation measurements in spectroscopy using j‑coupling simulations and investigate its effect on EPG water T2 mapping. Both ME-SE and STEAM T2 mapping methods to estimate the apparent fat T2 relaxation times are heavily influenced by J-coupling. As such the measured T2 relaxation time of fat using STEAM, appears shorter and using ME-SE appears longer, ranging between values of 30 and 140 ms.

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