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Abstract #1295

Trabecular Bone Imaging Using a 3D Adiabatic Inversion Recovery Prepared Ultrashort Echo Time Cones (3D IR-UTE Cones) Sequence

Ya-Jun Ma1, Liang Li1, Yanjun Chen1, Saeed Jerban1, Michael Carl2, Eric Y Chang1,3, and Jiang Du1

1Radiology, University of California, San Diego, San Diego, CA, United States, 2GE health care, San Diego, CA, United States, 3VA San Diego Healthcare System, San Diego, CA, United States

The trabecular bone is both functionally and biomechanically important for vertebrates, including humans. Evaluation of trabecular bone provides important information about risk of both osteoporosis and bone fracture. Direct MR imaging of trabecular bone is difficult due to its ultrashort T2* and low water content, resulting in little or no signal when conventional pulse sequences are used. The purpose of this study was to develop and evaluate a 3D adiabatic inversion recovery prepared UTE Cones (3D IR-UTE-Cones) sequence for volumetric imaging of trabecular bone ex vivo and in vivo on a clinical 3T scanner in clinically acceptable scan times.

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