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Abstract #1313

Assessment of the Angular Dependence of 3D Ultrashort Echo Time Cones Adiabatic T1ρ (3D UTE-Cones-AdiabT1ρ) Imaging

Mei Wu1,2, Yajun Ma1, Lidi Wan1, Tan Guo1, Saeed Jerban1, Hyungseok Jang1, Eric Y Chang1,3, and Jiang Du1

1Department of Radiology, University of California, San Diego, San Diego, CA, United States, 2Department of Radiology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou, China, 3Radiology Service, VA San Diego Healthcare System, San Diego, CA, United States

In this study we aimed to evaluate the magic angle sensitivity of the 3D UTE-Cones-AdiabT sequence in imaging the cadaveric human Achilles tendon and patellar cartilage samples on a clinical 3T scanner. The 3D UTE-Cones-AdiabT shows much reduced magic angle effect than regular T and T2*. The superficial layers show reduced magic angle effect compared to the middle and deep layers of articular cartilage. The 3D UTE-Cones-AdiabT sequence may provide magic angle insensitive evaluation of all the major knee joint tissues, thus providing a truly “whole-organ” approach for more accurate diagnosis of early OA.

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