Abstract #1313

Assessment of the Angular Dependence of 3D Ultrashort Echo Time Cones Adiabatic T1ρ (3D UTE-Cones-AdiabT1ρ) Imaging

Mei Wu^1,2, Yajun Ma¹, Lidi Wan¹, Tan Guo¹, Saeed Jerban¹, Hyungseok Jang¹, Eric Y Chang^1,3, and Jiang Du¹

¹Department of Radiology, University of California, San Diego, San Diego, CA, United States, ²Department of Radiology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou, China, ³Radiology Service, VA San Diego Healthcare System, San Diego, CA, United States

In this study we aimed to evaluate the magic angle sensitivity of the 3D UTE-Cones-AdiabT_1ρ sequence in imaging the cadaveric human Achilles tendon and patellar cartilage samples on a clinical 3T scanner. The 3D UTE-Cones-AdiabT_1ρ shows much reduced magic angle effect than regular T_1ρ and T2*. The superficial layers show reduced magic angle effect compared to the middle and deep layers of articular cartilage. The 3D UTE-Cones-AdiabT_1ρ sequence may provide magic angle insensitive evaluation of all the major knee joint tissues, thus providing a truly “whole-organ” approach for more accurate diagnosis of early OA.

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