Abstract #1329

Comparison of Single-Component and Multi-Component T2 Parameters and Mechanical Parameters of Human Patellar Cartilage at 3.0T

Matthew Grondin¹, Fang Liu², Michael Vignos¹, Jiang Du³, Corrinne Henak¹, and Richard Kijowski²

¹Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Radiology, University of California-San Diego, San Diego, CA, United States

Multi-component Driven Equilibrium Single Pulse Observation of T1 and T2 (mcDESPOT) was used to measure single-component T2 relaxation time (T2Single) and the fraction of the fast relaxing macromolecular bound water component (FF) of 24 human patellar cartilage samples at 3.0T. The cartilage samples underwent unconfined compression testing to measure linear modulus and energy dissipation at 0.01Hz and 10Hz. There were low and marginally statistically significant (p=0.052-0.084) negative correlations between T2Single and linear modulus and energy dissipation. There were moderate and statistically significant (p<0.002) positive correlations between FF and linear modulus and energy dissipation.

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