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Abstract #1330

MRI texture analysis of vertebral subchondral bone

Feifei Zeng1, Yunfei Zha2, and Yang Fan3

1Radiology, Renmin Hospital of Wuhan University, Wuhan, China, 2Renmin Hospital of Wuhan University, Wuhan, China, 3GE Healthcare China, Bejing, China

The purpose of this study is to assess the feasibility of MRI texture analysis as a method of quantifying vertebral subchondral bone (VSB) in early intervertebral disk degeneration (IDD). Sagittal T1WI, T2WI and T2* mapping images of lumbar vertebra were scanned at 3T MRI. Texture parameter values(mean, variance, skewness, correlation and entropy) of VSB (on T1WI) and T2* value of CEP were used for statistical evaluations. It was found that Significant differences in VSB texture parameters (mean ,variance and entropy) and T2* value of CEP were demonstrated between groups at the cephalic and caudal. Accordingly, texture parameter-mean showed significantly higher diagnostic accuracy than other texture parameters (variance and entropy) and T2* value for differentiating early IDD. MRI texture analysis can be used to assess human lumbar early IDD.

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