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Abstract #1332

Rapid Quantitative Simultaneous Bilateral Knee Imaging with Fully Automated Femoral Cartilage Analysis: Toward Knee Asymmetry Evaluation.

Marco Barbieri1,2, Arjun D. Desai2, Feliks Kogan2, Valentina Mazzoli2, Elka Rubin2, Gastone Castellani1, Garry E. Gold2,3, Brian A. Hargreaves2,3,4, and Akshay S. Chaudhari2

1Department of Physics and Astronomy, University of Bologna, Bologna, Italy, 2Department of Radiology, Stanford University, Stanford, CA, United States, 3Department of Bioengineering, Stanford University, Stanford, CA, United States, 4Department of Electrical Engineering, Stanford University, Stanford, CA, United States

Quantitative bilateral knee MRI and whole femoral cartilage analysis is currently limited by costs and scan time. We propose a rapid, simultaneous bilateral knee MRI protocol followed by a fully automated pipeline to perform quantitative T2 analysis of the whole femoral cartilage plate of both knees. Five healthy subjects and a subject with an ACL reconstruction were scanned in this study and the results demonstrated high scan-rescan repeatability and a good agreement between manual and automatic segmentation. The proposed acquisition method with automated analysis may make bilateral imaging more feasible and efficient for use in longitudinal and cross-sectional studies.

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