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Abstract #1365

Evaluation of the Activity of Ankylosing Spondylitis by Diffusion Kurtosis Imaging in Sacroiliitis

zhengyang zhou1, Jian He1, and Weibo Chen2

1Radiology, Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China, 2Philips Healthcare, Shanghai, China

Forty-four patients with AS underwent MRI including DKI to evaluate the disease activity of AS. Four disease activity states were chosen: inactive disease and moderate, high, and very high disease activity. The D and ADC values of sacroiliac joints in the active group were significantly higher, while the K value was significantly lower than those of the inactive group. The D value performed best in distinguishing different activity grades. The D and ADC values correlated positively, while the K value correlated negatively, with activity grade significantly. DKI of sacroiliac joints might be useful to evaluate the disease activity of AS.

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