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Abstract #1643

Cerebral Venous Oxygenation in the Human Fetuses With Enlarged Ventricles Using QSM

Brijesh Kumar Yadav1,2, Taotao Sun3, Feifei Qu2, E Mark Haacke1,2, Ling Jiang3, and Zhaoxia Qian3

1Department of Biomedical Engineering, Wayne State University, Detroit, MI, United States, 2Department of Radiology, Wayne State University, Detroit, MI, United States, 3Department of Radiology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

Fetal growth and development is a delicate process which relies on the optimal oxygen supply to the fetus. Obstruction to this supply might cause delayed myelination or white matter damage which in turn, may lead to enlargement of cerebral ventricles. therefore, cerebral venous oxygenation (SvO2) was estimated in second and third trimester fetuses with enlarge ventricles using quantitative susceptibility mapping. Average SvO2 was found to be 68.2%±5.1% and a decreasing trend in SvO2 across gestation was observed in the fetal cohort with enlarge ventricles.

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