This study focused on the correlation between amide proton transfer
(APT) imaging and IVIM, DCE MRI or 18F-FDG PET/CT in rectal cancer. Our
results showed a significant positive
correlation between APT signal intensity (APT SI) and SUVmax (p = 0.005, ρ = 0.547). No
significant correlation was shown between APT SI and IVIM (ADC, f, D* or D) or
DCE MRI parameters (Ktrans, Kep, Ve or
These results suggested that APT imaging reflects some metabolism of the rectal
cancer and may be useful for response prediction after chemotherapy.