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Abstract #1655

Reducing T2-shinethrough effects in prostate diffusion-weighted imaging with Stimulated Echo imaging

Yuxin Zhang1,2, Shane A Wells2, Benjamin L Triche2, Frederick Kelcz2, and Diego Hernando1,2

1Medical Physics, University of Wisconsin Madison, Madison, WI, United States, 2Radiology, University of Wisconsin Madison, Madison, WI, United States

The bright appearance of long-T2 tissues in DWI, termed “T2-shinethrough”, reduces the contrast between healthy tissue and cancer and is prominent in spin-echo based DWI acquisitions. In prostate DWI, the need to avoid T2-shinethrough has led to the acquisition of very high b-values in clinical practice, which may result in low SNR and other image artifacts. In this work, we have assessed the ability of stimulated-echo DWI to provide high contrast between PCa and healthy peripheral zone, without the need for high b-values. Preliminary results in 19 patients show reduced T2-shinethrough effects in stimulated-echo DWI compared with spin-echo DWI.

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