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Abstract #1667

Radiomics of Magnetic Resonance Imaging of Pancreas-Towards Improved Diagnosis and Management of Pancreatic Cancer

Touseef Ahmad Qureshi1, Lixia Wang1, Srinivas Gaddam2, Nan Wang1, Zixin Deng1, Simon Ahmad Lo2, Andrew Hendifar3, Zhaoyang Fan1, Stephen Pandol2, and Debiao Li1

1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Department of Gastroenterology, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 3Department of Gastrointestinal Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, United States

The MRI-based Radiomics of pancreas can identify several imaging-characteristics (e.g. texture, shape, signal intensity, etc.) that are distinct in healthy and cancerous pancreas. We performed MRI-based radiomics of pancreas to demonstrate that radiomics play an important rule to differentiate healthy and cancerous pancreas and can assist diagnosis and management of PC. Multiple statistical tests demonstrated that 18% of the total 250 radiomic features were significantly different between healthy and cancerous pancreas. These features have high diagnostic accuracy to detect PC. We conclude that MRI-based radiomics of pancreas can potentially have a future role in early detection, prognosis, and prediction of treatment outcome of PC.

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