Abstract #1697

A comparative study of MR elastography and intravoxel incoherent motion based on volumetric analysis in the evaluation of histological grade of Hepatitis B virus-related hepatocellular carcinoma

Qungang Shan¹, Yao Zhang¹, Tianhui Zhang¹, Bingjun He¹, Sudhakar K Venkatesh², Bing Wu³, Kevin J Glaser², Richard L Ehman², and Jin Wang¹

¹Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China, ²Department of Radiology, Mayo Clinic, Rochester, Armenia, ³MR Research China, GE Healthcare, Beijing, China

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver. Poorly differentiated HCC is associated with higher recurrence and worse survival compared with well and moderately differentiated HCC and preoperative prediction of histological grade is useful for deciding treatment strategy. We compared the value of MR elastography (MRE) and intravoxel incoherent motion (IVIM) in predicting the histological grade of hepatitis B virus (HBV)-related HCCs using volumetric analysis. Our results demonstrated that only mean tumor stiffness, and not ADC or IVIM metrics, could predict the histological grade of HCCs.

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