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Abstract #1698

Comparison of MR elastography and intravoxel incoherent motion for the prediction of hepatocellular carcinoma tumor capsule formation in hepatitis B virus-related patients using whole-tumor analysis

Yao Zhang1, Qungang Shan1, Sichi Kuang1, Bingjun He1, Jingbiao Chen1, Bing Wu2, Tianhui Zhang1, Ying Deng1, Kevin J Glaser3, Sudhakar K Venkatesh3, Richard L Ehman3, and Jin Wang1

1Department of Radiology, The third affiliated hospital of Sun Yat-sen University, Guangzhou, China, 2MR Research China, GE Healthcare, Beijing, China, 3Department of Radiology, Mayo Clinic, Rochester, MN, United States

Hepatocellular carcinoma (HCC) is the most common primary malignant hepatic tumor worldwide and the prognosis remains poor. Tumor capsule formation is a favorable factor for predicting invasiveness and prognosis. We explored the potential value of MR elastography(MRE)and intravoxel incoherent motion(IVIM)for the prediction of tumor capsule formation in patients with hepatitis B virus-related (HBV) HCCs using whole-tumor analysis. Results showed that mean tumor stiffness may be useful for the prediction of capsule formation of HCCs. The utility of the mean value of IVIM metrics may need to be further explored.

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