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Abstract #1700

Impacts of different b and TE values on quality of 3T diffusion-weighted imaging of the liver using a high gradient magnetic field: feasibility of ultrahigh b value of 3000

Keita Fukushima1, Katsuhiro Sano2, Haruhiko Machida3, Toshiya Kariyasu3, Isao Miyazaki1, Tatsuya Yoshioka1, Sanae Takahashi1, Saori Yuda1, Yuta Shimizu1, Takayuki Yonaha1, Akihito Nakanishi1, Hiroshi Kusahara4, Youhei Matsuoka4, Miho Kitamura4, Takao Yamamoto4, and Kenichi Yokoyama3

1Kyorin University Hospital, Tokyo, Japan, 2Diagnostic Imaging, Saitama medical University International medical Center, Saitama, Japan, 3Kyorin University School of Medicine, Tokyo, Japan, 4CANON MEDICAL SYSTEMS CORPORATION, Otawara, Japan

Diffusion-weighted imaging (DWI) with an ultrahigh b value is expected to improve assessment of tumor cellularity and fluid viscosity in the liver but can decrease signal-to-noise ratio (SNR) of the hepatic parenchyma. A state-of-the-art 3T MR scanner with the maximal gradient magnetic field of 100 mT/m can achieve sufficient SNR on liver DWI even at ultrahigh b value of 3000 with use of short TE. The present study using our original phantom and healthy volunteers shows that use of shorter TE significantly increased the SNR with preserved ADC value on DWI even at ultrahigh b value of 3000.

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