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Abstract #1868

Kaplan-Meier survival curves in breast cancer patients: contributions of nodal volume, tumor volume, residual disease, and response to chemotherapy

Renee Faith Cattell1, Pauline Huang1, James Kang1, Thomas Ren1, Ashima Muttreja1, Haifang Li1, Jules Cohen1, Lea Baer1, Cliff Bernstein1, Roxanne Palermo1, Sean Clouston1, and Timothy Duong1

1Stony Brook University, Stony Brook, NY, United States

The goal of our study was to evaluate whether pre- and post-chemotherapy nodal volume affects the survival profiles of breast cancer patients. In addition, we also evaluated these effects with respect to responders and non-responders to neoadjuvant chemotherapy. Comparison was made by analyzing the effects of tumor volume on survival profiles. We concluded that recurrence-free survival profile is dependent on axillary lymph node volume, and that non-responder patients with large nodes may need more vigorous treatment and follow up as they were associated with worse recurrence-free survival.

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