Meeting Banner
Abstract #1891

Joint Reconstruction of 1H and 19F gas MRI in the Human Lung

Arnd Jonathan Obert1,2, Marcel Gutberlet1,2, Andreas Voskrebenzev1,2, Gesa Pöhler1,2, Robert Grimm3, Frank Wacker1,2, and Jens Vogel-Claussen1,2

1Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, 2Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany, 3Siemens Healthcare, Erlangen, Germany

Due to its low costs, high inertness and applicability at thermal polarization, fluorinated gases are promising tracers for imaging lung ventilation using fluorine magnetic resonance imaging. In this work, the joint reconstruction of proton density and 19F ventilation images in the human lung is shown. To exploit the structural similarity of both imaging modalities, a regularized reconstruction is used, minimizing the parallel level sets. Quantitative analysis of the reconstruction performance could be achieved by retrospective undersampling of data collected during a 2.5-minute breath hold. Furthermore, computation of VDP maps has been analyzed using joint reconstruction in three COPD patients.

This abstract and the presentation materials are available to members only; a login is required.

Join Here