Recently, 3D O2-enhanced MRI at 3T system is recently developed by Cannon Medical Systems Corporation. On the other hands, no one directly compare this technique with quantitatively assessed CT for smoking-related COPD assessment. We hypothesized that 3D O2-enhanced MRI has a potential for quantitative assessment of morphological changes due to smoking-related COPD as well as quantitatively assessed thin-section CT. The purpose of this study was to prospectively and directly compare the quantitative capability for pulmonary functional loss assessment and clinical stage classification between 3D O2-enhanced MRI and thin-section CT in smokers.
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