There are currently no sensitive measures for kidney disease progression in Autosomal Recessive Polycystic Kidney Disease (ARPKD). In this study, T1 and T2 relaxation times and Apparent Diffusion Coefficient (ADC)) were evaluated for their sensitivity to detect ARPKD progression in the bpk mouse model of ARPKD, which closely mimics human ARPKD kidney disease. Mean kidney T2 showed a significant correlation with both age and kidney volume. T1 and ADC showed no significant correlations. These results suggest that renal T2 relaxometry may be a viable marker for ARPKD kidney disease progression in vivo.