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Abstract #1912

Use of 3D Arterial Spin Labeling to Evaluate Renal Perfusion in Patients with Chronic Kidney Disease

Shuohui Yang1, Fang Lu1, Jing Yang2, Songhua Zhan1, Kuehn Bernd3, Caixia Fu4, Mengxiao Liu4, and Zhongshuai Zhang4

1Radiology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China, 2Nephrology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China, 3MR Applications Development, Siemens Healthcare, Erlangen, Germany, 4MR Applications Development, Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China

The purpose of this study is to evaluate the effectiveness of 3D PASL and 3D pCASL in assessing RBF in both the renal cortex and medulla of CKD patients and healthy volunteers. The results showed that RBF maps derived from 3D pCASL had significantly better image quality than RBF maps derived from 3D PASL. 3D pCASL has the potential to become a novel non-invasive and non-contrast MRI technique to assess renal cortical and medullary perfusion.

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