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Abstract #1921

The Effect of Water Loading on Renal Diffusion Parameters with Triexponential Analysis

Yuki Koshino1, Naoki Ohno2, Tosiaki Miyati2, Kotaro Yoshida3, Satoshi Kobayashi1,2,3, Naoki Hori1, Yukihiro Matsuura1, and Toshifumi Gabata3

1Department of Radiological Technology, Kanazawa University Hospital, Kanazawa, Japan, 2Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, 3Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan

To assess the response of water loading on diffusion parameters in the renal tissue, we evaluated renal diffusion coefficients with tri- and biexponential analyses before and after water loading. Our results showed that slow-restricted diffusion coefficient with triexponential analysis in the renal medulla was significantly increased after water loading, whereas none of the diffusion parameters with biexponential analysis significantly changed. Diffusion analysis with triexponential function could enable us to obtain more detailed information on renal function.

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