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Abstract #1920

MRI based Renal Resistivity Index in Chronic Kidney Disease

Muditha S. Bandara1, Hasith E. Perera1, Chirath Sulalith2, Aruna Pallewatte2, and Janaka P. Wansapura1

1Department of Physics, University of Colombo, Colombo 3, Sri Lanka, 2Department of Radiology and Neuroradiology, National Hospital of Sri Lanka, Colombo, Sri Lanka

We show, for the first time, the feasibility of using MRI based renal resistivity index (RRI) to differentiate patients with chronic kidney disease from healthy subjects. RRI and the Pulse Wave Velocity (PWV) of the abdominal aorta were calculated using quantitative phase contrast imaging. The RRI was significantly higher in CKD patients (0.71 ± 0.07) than in the healthy subjects (0.65 ± 0.04). The mean PWV was also significantly higher in CKD patient indicating hypertension and arterial stiffness in CKD. The high RRI in CKD indicates restriction to perfusion, probably due to of tubulointerstitial fibrosis in the kidney.

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