Abstract #1919

Use of Intravoxel incoherent motion imaging in assessment of different degrees of renal lesions: alterations in diffusion and perfusion in animal study with renal lesions

Zhiheng Feng¹, Hanjing Kong¹, Chengyan Wang², Xiaodong Zhang³, Min Yang³, Jue Zhang¹, and Xiaoying Wang³

¹Peking University, Beijing, China, ²Shanghai Jiao Tong University, Shanghai, China, ³Peking University First Hospital, Beijing, China

IVIM DWI (intravoxel incoherent motion diffusion-weighted image) is a noninvasive imaging technology capable of simultaneously detecting diffusion and perfusion characteristics of renal tissue . This study investigates the feasibility of IVIM DWI in evaluating different degree of renal lesions. IVIM DWI was performed on sixteen rabbits with different degree of renal lesions, which were confirmed by the corresponding pathological results. A noticeable change of renal diffusion and perfusion can be clearly observed in different degrees of renal lesions. There exists significant difference in f values among four groups with different severity in renal lesions.

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