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Abstract #1935

3.0T MRI with IDEAL-IQ sequence for Assessment of pancreatic fatty infiltration During Progression of T2DM Animal Model

Yidi Chen1 and Liling Long1

1Radiology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

This study was undertaken to determine the accuracy of pancreatic MR imaging by proton density fat fraction measurements with the iterative decomposition of water and fat with the echo asymmetry and least-squares estimation quantitation (IDEAL-IQ) sequences, and to explore changes of pancreatic fat content in a diabetic animal model. We found that estimation of pancreatic fat content by pulse sequence imaging is accurate and reproducible across readers. Further, greater pancreatic fat infiltration was observed in diabetic animals and it is related to the level of fasting blood glucose, which supports its use as a biomarker for diabetes risk.

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