Abstract #1977

Left and Right Heart Ventricular-Vascular Coupling in Pulmonary Venous Hypertension

Mohammed S.M. Elbaz¹, Vamsi Reddy¹, Muhannad Abbasi¹, Roberto Sarnari¹, Daniel Gordon¹, Michael Cuttica², Benjamin Freed³, Michael Markl¹, and James Carr¹

¹Radiology, Northwestern University, Chicago, IL, United States, ²Pulmonary and Critical Care, Northwestern University, Chicago, IL, United States, ³Cardiology, Northwestern University, Chicago, IL, United States

Pulmonary Venous hypertension (PVH) is a life-threatening disease with a complex etiology that involves both the left and right heart. However, the mechanism of left heart dysfunction as a precursor to changes in right heart hemodynamics and dysfunction remains unclear. Here, we assessed the complex functional-hemodynamic coupling between the left and right heart and pulmonary arteries. We investigated the association of LV and RV function with advanced 4D Flow MRI hemodynamic metrics of volumetric viscous energy loss, kinetic energy and vorticity in the right heart and pulmonary arteries in PVH patients.

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