Abstract #2015

Accelerating modified Look-Locker inversion recovery (MOLLI): Shortened inversion-recovery-based myocardial T1 mapping schemes

Li Huang¹, Radhouene Neji^1,2, Muhammad Sohaib Nazir¹, John Whitaker¹, Filippo Bosio¹, Amedeo Chiribiri¹, Reza Razavi¹, and Sébastien Roujol¹

¹School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom, ²MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Abnormal native myocardial T1 times are associated with a variety of cardiomyopathies, and are widely measured by inversion-recovery-based myocardial T1 mapping techniques such as modified Look-Locker inversion recovery (MOLLI). These sequences are limited in patients with severe breathholding difficulties for relatively long duration of breathholds. In this work, we sought to develop and characterize shortened schemes using less amount of T1-weighted images to reduce their sensitivity to imperfect breathholds.

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