Long acquisition window in myocardial T1 mapping degrades the image quality. Physiological motion induced fluctuations along the parametric direction corrupt the similarity among T1-weighted images and adversely impact the performance of the compressed sensing-based methods. In this study, we propose a two-layer sparsifying transform (MO2) combined with motion correction to shorten the acquisition window of myocardial T1 mapping. Results showed that the proposed method enabled higher acceleration factor. The resulting shorter acquisition window and fewer RF saturation pulses increased the accuracy of the native T1 measurement.
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