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Abstract #2014

Myocardial T1 mapping with Shortened Acquisition Window using a two-layer Sparsifying Transform

Yanjie Zhu1,2, Dong Liang1, Maryam Nezafat2, Chong Duan2, and Reza Nezafat2

1Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 2Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States

Long acquisition window in myocardial T1 mapping degrades the image quality. Physiological motion induced fluctuations along the parametric direction corrupt the similarity among T1-weighted images and adversely impact the performance of the compressed sensing-based methods. In this study, we propose a two-layer sparsifying transform (MO2) combined with motion correction to shorten the acquisition window of myocardial T1 mapping. Results showed that the proposed method enabled higher acceleration factor. The resulting shorter acquisition window and fewer RF saturation pulses increased the accuracy of the native T1 measurement.

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