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Abstract #2013

Comparison of cardiac function, morphology and tissue characteristics between two subtypes of primary aldosteronism: a 3 Tesla MR study

Satoshi Higuchi1, Hideki Ota1, Kazumasa Seiji1, Yuta Tezuka2, Ryo Morimoto2, Tatsuya Nishii3, Tetsuya Fukuda3, and Kei Takase1

1Diagnostic Radiology, Tohoku university hospital, Sendai, Japan, 2Endocrinology, Tohoku university hospital, Sendai, Japan, 3Radiology, National cerebral and cardiovascular center, Suita, Japan

The purpose of this study is to compare cardiac morphology, function and tissue characteristics between patients with two subtypes of primary aldosteronism (PA), aldosterone-producing adenoma (APA) and bilateral hyperaldosteronism (BHA). One-hundred-and-forty-three consecutive PA patients underwent 3T MR examinations including cine, late gadolinium enhancement and pre- and post-contrast T1 mapping. APA group demonstrated higher myocardial native T1 and left-ventricular end-diastolic volume index than BHA after controlling for patients’ demographic data. The results indicate that APA group, with higher hormonal activity than BHA, may be suffered from LV volume overload and myocardial fibrosis or edema as compared with BHA group.

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