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Abstract #2017

Hybrid PET/MR in Cardiac Sarcoidosis: A segmental analysis.

Emily A Aherne1, Ali Serhal1, Ryan J Avery1,2, Alexander Ruh3, Louise M Collins3, Hatice Savas2, Gary Dillehay2, and James C Carr1

1Cardiovascular Imaging, Northwestern University, Chicago, IL, United States, 2Nuclear Imaging, Northwestern University, Chicago, IL, United States, 3Radiology, Northwestern University, Chicago, IL, United States

Cardiac sarcoidosis (CS) is difficult to clinically diagnose but associated with high morbidity and mortality. Hybrid PET/MR has been shown to provide clinicians with complementary data regarding both the pattern and activity of myocardial disease. We performed a segmental quantitative analysis of MR parameters on 30 patients including T1 and T2 mapping, ECV, scar and strain acquired as part of a hybrid PET/MR study to evaluate characteristic patterns of imaging in this heterogeneous disease process. Scar quantification had a significant positive correlation with T1 and ECV and was negatively correlated with strain.

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