Abstract #2018

Validation of Fully Automatic SegmenTal Relaxometry (FASTR) in patients post myocardial infarction

Venkat Ramanan¹, Idan Roifman², Xiuling Qi¹, LaBonny Biswas¹, Graham Wright^1,3, and Nilesh Ghugre^1,3

¹Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada, ²Cardiology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, ³Medical Biophysics, University of Toronto, Toronto, ON, Canada

T1 mapping has started to be used for both diffuse and focal diseases of the heart and recently in multi-slice mode to investigate the regional (segmental) variations in T1 and ECV. The processing usually involves contouring the endo and epicardial boundaries manually, which could be cumbersome especially for high-volume studies. Recently, we presented a fully automatic approach (FASTR), to calculate T1 and ECV values segment-wise. Here we present the initial validation of our technique in patients post myocardial infarction. FASTR is comparable to an expert-driven contour and has low bias and similar variability in comparison to inter-observer analysis.

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