To investigate if zero-echo-time magnetic resonance angiography (zTE-MRA) is feasible in the characterization of intracranial atherosclerotic disease, we measured in this study a large population with atherosclerotic disease confirmed clinically. The acquired zTE-MRA images were thus compared systematically with those using time-of-flight (TOF)-MRA technique. Serving digital subtraction angiography (DSA) as a reference, zTE-MRA showed comparable imaging quality with DSA in the aspect of flow signal in the parent artery and higher signal intensity with less artifact than TOF-MRA. We therefore demonstrated that zTE-MRA could be a promising technique and further applied in the clinic routinely for patients with atherosclerotic disease.
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