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Abstract #2091

Plaque feature analysis using a joint method of QSM and water-fat separation

Pascal Peter Richard Ruetten1, Alison Cluroe2, Ammara Usman1, Jonathan H Gillard1, and Martin J Graves3

1Department of Radiology, University of Cambridge, Cambridge, United Kingdom, 2Department of Histopathology, Cambridge University Hospital NHS Trust, Cambridge, United Kingdom, 3Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom

In this work we investigated the feasibility of using a joint method of water-fat separation and Quantitative Susceptibility Mapping to characterize carotid artery plaques. The combination of both methodologies was able to detect strong changes in susceptibility, to detect plaque calcification, and also detect changes in the local fat fraction of the plaques in order to identify a lipid core.

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