Abstract #2091

Plaque feature analysis using a joint method of QSM and water-fat separation

Pascal Peter Richard Ruetten¹, Alison Cluroe², Ammara Usman¹, Jonathan H Gillard¹, and Martin J Graves³

¹Department of Radiology, University of Cambridge, Cambridge, United Kingdom, ²Department of Histopathology, Cambridge University Hospital NHS Trust, Cambridge, United Kingdom, ³Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom

In this work we investigated the feasibility of using a joint method of water-fat separation and Quantitative Susceptibility Mapping to characterize carotid artery plaques. The combination of both methodologies was able to detect strong changes in susceptibility, to detect plaque calcification, and also detect changes in the local fat fraction of the plaques in order to identify a lipid core.

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