Abstract #2107

Fast and reproducible right ventricular longitudinal strain is a sensitive marker of pulmonary arterial hypertension

Shuang Leng¹, Yang Dong², Xiaoke Shang³, Xiaodan Zhao¹, Ru-San Tan^1,4, Wen Ruan¹, Gangcheng Zhang⁵, John C. Allen⁴, Angela S. Koh^1,4, Bryant Jennifer¹, Lynette Teo^6,7, Ping Chai^7,8, James W. Yip^7,8, Jonathan Yap¹, Soo Teik Lim^1,4, Marielle V Fortier^4,9, Teng Hong Tan^4,9, Ju Le Tan^1,4, Yucheng Chen², and Liang Zhong^1,4

¹National Heart Centre Singapore, Singapore, Singapore, ²West China Hospital, Chengdu, China, ³Wuhan Union Hospital, Wuhan, China, ⁴Duke-NUS Medical School, Singapore, Singapore, ⁵WuHan Asia Heart Hospital, Wuhan, China, ⁶National University Hospital, Singapore, Singapore, ⁷National University of Singapore, Singapore, Singapore, ⁸National University Heart Centre, Singapore, Singapore, ⁹KK Women's and Children's Hospital, Singapore, Singapore

Survival of patients with pulmonary arterial hypertension (PAH) is closely related to right ventricular (RV) function. This study aims to introduce a fast global longitudinal strain (GLS) measurement for RV function assessment by automatically tracking the distance variation between tricuspid annular insertion points and the RV apical epicardium. The intra- and inter-observer variation of coefficients range from 3.9% to 5.7% with processing time averaging 32 ± 8 seconds per subject. Results demonstrate that lower fast GLS measurements are closely related to impaired RV function and higher risks in PAH.

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