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Abstract #2107

Fast and reproducible right ventricular longitudinal strain is a sensitive marker of pulmonary arterial hypertension

Shuang Leng1, Yang Dong2, Xiaoke Shang3, Xiaodan Zhao1, Ru-San Tan1,4, Wen Ruan1, Gangcheng Zhang5, John C. Allen4, Angela S. Koh1,4, Bryant Jennifer1, Lynette Teo6,7, Ping Chai7,8, James W. Yip7,8, Jonathan Yap1, Soo Teik Lim1,4, Marielle V Fortier4,9, Teng Hong Tan4,9, Ju Le Tan1,4, Yucheng Chen2, and Liang Zhong1,4

1National Heart Centre Singapore, Singapore, Singapore, 2West China Hospital, Chengdu, China, 3Wuhan Union Hospital, Wuhan, China, 4Duke-NUS Medical School, Singapore, Singapore, 5WuHan Asia Heart Hospital, Wuhan, China, 6National University Hospital, Singapore, Singapore, 7National University of Singapore, Singapore, Singapore, 8National University Heart Centre, Singapore, Singapore, 9KK Women's and Children's Hospital, Singapore, Singapore

Survival of patients with pulmonary arterial hypertension (PAH) is closely related to right ventricular (RV) function. This study aims to introduce a fast global longitudinal strain (GLS) measurement for RV function assessment by automatically tracking the distance variation between tricuspid annular insertion points and the RV apical epicardium. The intra- and inter-observer variation of coefficients range from 3.9% to 5.7% with processing time averaging 32 ± 8 seconds per subject. Results demonstrate that lower fast GLS measurements are closely related to impaired RV function and higher risks in PAH.

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