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Abstract #2108

A fast and semi-automated approach for assessing left ventricular longitudinal strain with cine cardiovascular magnetic resonance imaging in heart failure with preserved and mid-range ejection fraction

Shuang Leng1, Xiaodan Zhao1, Ru-San Tan1,2, Angela S. Koh1,2, Bryant Jennifer1, Jun-Mei Zhang1,2, Ris Low1, David Sim1,2, John C. Allen2, Hak Chiaw Tang1,2, and Liang Zhong1,2

1National Heart Centre Singapore, Singapore, Singapore, 2Duke-NUS Medical School, Singapore, Singapore

This study aimed to study the left ventricular (LV) longitudinal deformation by a semi-automated and rapid assessable strain parameter (i.e. global longitudinal strain, GLS) with standard cardiovascular magnetic resonance images. Study population consisted of 50 normal controls, 60 patients with heart failure (10 HFpEF, 10 HFmrEF and 40 HFrEF) and 10 patients with hypertrophic cardiomyopathy. Average processing time of the fast strain measurement method was 78 ± 8 seconds per case with intra- and inter-observer variations ranging from 3.3% to 5.8%. Results demonstrated that the fast and reproducible GLS is a powerful independent predictor in patients with HFpEF and HFmrEF.

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