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Abstract #2111

Four-dimensional whole-heart cine imaging with isotropic resolution in one single breath-hold: initial results

Davide Piccini1,2,3, Lorenzo Di Sopra2, Jérôme Yerly2,4, Gabriella Vincenti5, Tobias Rutz5, Juerg Schwitter5, and Matthias Stuber2,4

1Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 2Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 3LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 4Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, 5Division of Cardiology and Cardiac MR Center, University Hospital of Lausanne (CHUV), Lausanne, Switzerland

In cardiac MRI, the evaluation of left ventricular ejection fraction (LVEF) is based on well-defined protocols and involves a stack of 2D cine images acquired during multiple breath-holds. This procedure is time-consuming and may result in suboptimal coverage and inter-slice misregistration. Here, a novel acquisition protocol for 3D cine imaging with whole-heart coverage in one single breath-hold with isotropic spatial resolution is described and tested in 10 subjects in comparison to the 2D gold-standard. All 2D datasets and 9/10 3D datasets were considered adequate for LVEF calculation. Bland-Altman analysis of LVEF shows good agreement and no bias between the two measurements.

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