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Abstract #2175

Non-contrast, free-breathing pulmonary perfusion imaging in pediatric patients with congenital heart disease using multi-slice FAIR at 1.5T

Joshua S. Greer1,2, Vasu Gooty1, Animesh Tandon1,2, Gerald F. Greil1,2,3, Tarique Hussain1,2,3, and Ananth J. Madhuranthakam2,3

1Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States, 2Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Congenital heart disease (CHD) is associated with anatomical abnormalities in the pulmonary arteries (PAs) which can result in asymmetric flow to the lungs, as well as an overall reduction in lung perfusion. Non-contrast pulmonary perfusion imaging using arterial spin labeling has the potential to provide both quantitative perfusion maps as well as a measure of asymmetric pulmonary blood flow. In this study, multi-slice, free-breathing pulmonary perfusion imaging is demonstrated using the FAIR technique for full coverage of the lungs, and flow measurements are compared with the standard phase contrast measurement approach.

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