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Abstract #2209

Detecting Hemorrhagic Myocardial Infarction with Dark Blood T2*: Experimental Findings

Xingmin Guan1,2, Hsin-Jung Yang1, Jane Sykes3, John Butler3, Guan Wang1, Frank S Prato3, and Rohan Dharmakumar1,2

1Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2University of California, Los Angeles, Los Angeles, CA, United States, 3Lawson Health Research Institute, London, ON, Canada

Dark-blood prepared T2* MRI has become the preferred method for examining global myocardial iron overloading. However, whether dark-blood prepared T2* MRI is superior to bright-blood T2* MRI for the detection of hemorrhagic myocardial infarctions is not known. Here we show that, compared to bright-blood T2* MRI, dark-blood prepared T2* MRI yields significantly lower image contrast for detecting hemorrhagic myocardial infarction at 1.5T and 3.0T. We conclude that unless this loss in image contrast is mitigated, dark-blood T2* MRI may not provide adequate sensitivity for detecting hemorrhagic myocardial infarctions.

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