Meeting Banner
Abstract #2216

Pulmonary circulation time measurements and lung blood volume estimation in mice by magnetic particle imaging and magnetic resonance imaging

Michael Gerhard Kaul1, Johannes Salamon1, Caroline Jung1, Matthias Graeser2,3, Harald Ittrich1, Gerhard Adam1, and Kersten Peldschus1

1Department for Interventional and Diagnistic Radiology and Nuclear Medicine, University Medical Center Hamburg, Hamburg, Germany, 2Section for Biomedical Imaging, University Medical Center Hamburg, Hamburg, Germany, 3Institute for Biomedical Imaging, Hamburg University of Technology, Hamburg, Germany

Pulmonary circulation time and/or the blood volume of the lungs can be used to depict pathologic changes. The purpose of our study was to determine the circulation time of a bolus of superparamagnetic iron oxide nanoparticles through the lungs by MPI and to estimate the blood volume of the lungs supplemented by cardiac MRI. The pulmonary circulation times were 907 ± 141 ms. The determination of the blood volume revealed a volume of 233 ± 48 µL.

This abstract and the presentation materials are available to members only; a login is required.

Join Here