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Abstract #2219

Quantitative High-Resolution Myocardial First-Pass Perfusion Imaging of CO2-Induced Vasodilation in Rat

Grzegorz Kwiatkowski1 and Sebastian Kozerke1

1Institute for Biomedical Engineering, ETH & University of Zurich, Zurich, Switzerland

Respiratory-induced acidosis is an emerging alternative to induce increased coronary blood flow necessary to facilitate the quantification of the stress myocardial blood flow and hence myocardial perfusion reserve. The aim of this study was to quantify the pharmacokinetic effect of the CO2 gas challenge on myocardial perfusion in rats using a high-resolution first pass perfusion CMR.

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