Gliomas are a class of aggressive brain tumors with a low survival rate. New biomarkers are needed to monitor tumor progression and response to treatment. Our goal was to compare the effectiveness of operator-independent LCModel analysis for HRMAS NMR spectra acquired from histologically confirmed glioma tissue (n=14) using both FID and CPMG pulse sequences. The CRLBs of lactate and myo-inositol were significantly lower for spectra acquired with the CPMG compared to the FID sequence. Relevant glioma metabolites were quantified with LCModel from most spectra acquired with CPMG but not FID.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords