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Abstract #2288

Multi-exponential decay of dipolar order in spinal cord and its correlation to spin diffusion

Uzi Eliav1, Gil Navon1, and Peter J. Basser2

1School of Chemistry, Tel Aviv University, Tel Aviv, Israel, 2SQITS/NICHD/, National Institutes of Health, Bethesda, MD, United States

Images obtained by inhomogeneous magnetization transfer were analyzed using models involving Zeeman and dipolar orders. These orders are affected by spin diffusion and relaxation. In the current study a method that enables the measurement of these processes in spinal cord by the same pulse sequence is presented. Magnetization transfer time (MT, spin diffusion) between CH2 groups is ~0.1ms while the MT between them and CH3 groups is much slower (~2ms). The dipolar order is found to decay by three exponentials process (0.11, 0.86, 11.4ms). The fastest decaying component is compatible with the spin diffusion between the CH2.

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