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Abstract #2289

Magnetic Resonance Spectrum Simulator (MARSS): Software for Fast and Reliable Simulation of Spin Systems

Karl Landheer1, Kelley M. Swanberg1, and Christoph Juchem1,2

1Biomedical Engineering, Columbia University, New York, NY, United States, 2Radiology, Columbia University, New York, NY, United States

Accurate density matrix simulation of nuclear spin systems is critical for quantifying magnetic resonance spectroscopy (MRS) data, as well as for simulation studies designed to optimize acquisition parameters. Although a variety of packages exist to achieve this result, no currently available software is capable of computing a large number of spatial points in a reasonable time frame. Here we present and experimentally validate a novel MATLAB-based software package able to compute complex spin systems, including those exhibiting scalar coupling like GABA, for 643 spatial points within 25 minutes.

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