Abstract #2313

Association between Metabolism Measured by PET/CT and Vascular Parameters Measured by Dynamic Contrast Enhanced MRI in Spinal Lesions

Jiahui Zhang¹, Enlong Zhang¹, Yanyan Zhang², Yongye Chen¹, Ning Lang¹, Hon J Yu³, Huishu Yuan¹, and Min-Ying Lydia Su³

¹Department of Radiology, Peking University Third Hospital, Beijing, China, ²Department of Nuclear Medicine, Peking University Third Hospital, Beijing, China, ³Department of Radiological Sciences, University of California, Irvine, CA, United States

A total of 49 patients with spinal lesions receiving DCE-MRI and 18F-FDG PET/CT were analyzed. The ROI was manually placed on strongly enhanced area on MRI to measure DCE enhancement kinetics, and from which the wash-in and maximum enhancement ratio, wash-out slope, Ktrans and kep were extracted. SUVmax was measured from the corresponding lesion on FDG uptake map. The results showed that vascular parameters measured from DCE-MRI were not correlated with glucose metabolism measured by PET/CT; therefore, they represent different aspects of lesion, and may be combined for better staging or predicting prognosis rather than being used for diagnosis.

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