Abstract #2331

Respiratory motion variability in 4D-MRI for MR-guided radiotherapy

Bjorn Stemkens^1,2, Max van Riel^1,3, Tom Bruijnen¹, Jan JW Lagendijk¹, Cornelis AT van den Berg¹, and Rob HN Tijssen¹

¹Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, ²MR Code B.V., Zaltbommel, Netherlands, ³Biomedical Engineering, University of Technology Eindhoven, Eindhoven, Netherlands

Respiratory-induced motion of abdominal tumors can lead to displacements up to five centimeter, making radiotherapy treatments very challenging. The respiratory motion can be characterized by a 4D-MRI, acquired prior to treatment. In this study we investigate how long the 4D-MRI is valid for after acquisition. Additionally, the longitudinal validity of a motion model, derived from the 4D-MRI is assessed.

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