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Abstract #2331

Respiratory motion variability in 4D-MRI for MR-guided radiotherapy

Bjorn Stemkens1,2, Max van Riel1,3, Tom Bruijnen1, Jan JW Lagendijk1, Cornelis AT van den Berg1, and Rob HN Tijssen1

1Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, 2MR Code B.V., Zaltbommel, Netherlands, 3Biomedical Engineering, University of Technology Eindhoven, Eindhoven, Netherlands

Respiratory-induced motion of abdominal tumors can lead to displacements up to five centimeter, making radiotherapy treatments very challenging. The respiratory motion can be characterized by a 4D-MRI, acquired prior to treatment. In this study we investigate how long the 4D-MRI is valid for after acquisition. Additionally, the longitudinal validity of a motion model, derived from the 4D-MRI is assessed.

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