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Abstract #2336

4DMRI-based abdominal corset study for radiotherapy purposes

Kai Dolde1,2,3, Christian Dávid3,4, Gernot Echner1,2, Ralf Floca2,5, Clemens Hentschke2,5, Nina Niebuhr1,2,3, Kai Ohmstedt1,2,6, Nami Saito7, Merkur Alimusaj8, Beate Flügel8, and Asja Pfaffenberger1,2

1Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2Heidelberg Institute for Radiooncology (HIRO), National Center for Radiation Research in Oncology (NCRO), Heidelberg, Germany, 3Department of Physics and Astronomy, Heidelberg University, Heidelberg, Germany, 4X-Ray Imaging and Computed Tomography, German Cancer Research Center (DKFZ), Heidelberg, Germany, 5Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany, 6Department of Medicine, Heidelberg University, Heidelberg, Germany, 7Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany, 8Center for Orthopedic and Trauma Surgery, Heidelberg University Hospital, Heidelberg, Germany

Abdominal organ motion provides challenges for radiotherapy treatments, leading to inhomogeneous dose distributions with over- and underdosage regions in the target volume. Repeated 4D-MRI acquisitions, allow to analyze inter- and intrafractional spatial motion. The aim of this study was to investigate the impact of abdominal corsets for motion reduction purposes, based on repeated 4D-MRI data sets. We found pronounced reductions in cranio-caudal and anterior-posterior direction using corsets, which additionally lead to more reproducible motion amplitudes. Lower amplitudes and better reproducibility are beneficial for radiotherapy and could lead to smaller irradiation margins and dose reductions to healthy tissue.

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