Abstract #2336

4DMRI-based abdominal corset study for radiotherapy purposes

Kai Dolde^1,2,3, Christian Dávid^3,4, Gernot Echner^1,2, Ralf Floca^2,5, Clemens Hentschke^2,5, Nina Niebuhr^1,2,3, Kai Ohmstedt^1,2,6, Nami Saito⁷, Merkur Alimusaj⁸, Beate Flügel⁸, and Asja Pfaffenberger^1,2

¹Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Heidelberg Institute for Radiooncology (HIRO), National Center for Radiation Research in Oncology (NCRO), Heidelberg, Germany, ³Department of Physics and Astronomy, Heidelberg University, Heidelberg, Germany, ⁴X-Ray Imaging and Computed Tomography, German Cancer Research Center (DKFZ), Heidelberg, Germany, ⁵Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany, ⁶Department of Medicine, Heidelberg University, Heidelberg, Germany, ⁷Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany, ⁸Center for Orthopedic and Trauma Surgery, Heidelberg University Hospital, Heidelberg, Germany

Abdominal organ motion provides challenges for radiotherapy treatments, leading to inhomogeneous dose distributions with over- and underdosage regions in the target volume. Repeated 4D-MRI acquisitions, allow to analyze inter- and intrafractional spatial motion. The aim of this study was to investigate the impact of abdominal corsets for motion reduction purposes, based on repeated 4D-MRI data sets. We found pronounced reductions in cranio-caudal and anterior-posterior direction using corsets, which additionally lead to more reproducible motion amplitudes. Lower amplitudes and better reproducibility are beneficial for radiotherapy and could lead to smaller irradiation margins and dose reductions to healthy tissue.

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