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Abstract #2344

Extended texture analysis of unenhanced T1 and T2 sequences on whole body MRI for evaluation of response to chemotherapy in patients with multiple myeloma

Kaspar Ekert1, Christopher Kloth2, and Marius Horger1

1Diagnostic and Interventional Radiology, University Hospital Tubinga, Tubinga, Germany, 2Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany

Extended texture analysis of unenhanced T1 and T2 sequences on whole body MRI for evaluation of response to chemotherapy in patients with multiple myeloma. Patients in a pre-treatment and post-treatment setting using a standardized imaging protocol and a standardized hematological and clinical surveillance were included. 107 features, based on the pyradiomics library, were analyzed for the main medullary lesion in myeloma patients. Extracted texture features were able to discriminate between responders and non-responders at follow-up in particular when using T2-imaga data.

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