Abstract #2364

Cluster analysis of IVIM parameter maps reveals tumor subregions of different proliferative status

Oscar Jalnefjord^1,2, Mikael Montelius¹, Jonathan Arvidsson^1,2, Eva Forssell-Aronsson^1,2, Göran Starck^1,2, and Maria Ljungberg^1,2

¹Department of Radiation Physics, University of Gothenburg, Gothenburg, Sweden, ²Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden

Tumors are often heterogeneous, which can be seen with various imaging techniques. Even so, analysis based on quantitative imaging is often restrained to average tumor parameter values. In this study we used cluster analysis to identify tumor subregions based on IVIM parameter maps. The tumor subregions showed strong agreement with proliferative status as derived from histological analysis.

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