Abstract #2395

TrueFISP MRI assay for fast & reliable tumor stage classification in carcinogen induced orthotopic bladder cancer

Daniele Procissi¹, Alexander P Glaser ², Yanni Yu³, and Joshua J Meeks³

¹Radiology & Biomedical Engineering, Northwestern University, Chicago, IL, United States, ²Surgery, Division of Urology, Northshore University Health System, Evanston, IL, United States, ³Urology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States

Using a TrueFISP sequence we implemented a non-invasive assay for stage classification of bladder tumors using a orthotopic murine bladder cancer model. Because generation of this tumor model is achieved by administration of carcinogenic agents it is naturally heterogeneous. The imaging method proposed allows accurate assessment of tumor burden and provides a tool for randomization to experimental treatments.

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