Abstract #2477

31P MRSI of the human brain at 9.4 T: Metabolic imaging applying low-rank denoising

Loreen Ruhm^1,2, Johanna Dorst^1,2, Nikolai Avdievich¹, Andrew Wright^1,2, Christian Mirkes¹, Jonas Bause^1,3, Klaus Scheffler^1,3, and Anke Henning¹

¹High-Field MR Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, ²IMPRS for Cognitive and Systems Neuroscience, Eberhard-Karls University of Tübingen, Tübingen, Germany, ³Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

³¹P MRSI enables the imaging of important components of the energy and cell membrane metabolism but suffers from low intrinsic sensitivity. In this work, we tested the LORA and CLORA low-rank noise reduction approaches to improve the quality of 3D ³¹P MRSI data and present first in vivo results for ³¹P MRSI acquired from the human brain at ultrahigh field strength of 9.4 T.

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