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Abstract #2477

31P MRSI of the human brain at 9.4 T: Metabolic imaging applying low-rank denoising

Loreen Ruhm1,2, Johanna Dorst1,2, Nikolai Avdievich1, Andrew Wright1,2, Christian Mirkes1, Jonas Bause1,3, Klaus Scheffler1,3, and Anke Henning1

1High-Field MR Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 2IMPRS for Cognitive and Systems Neuroscience, Eberhard-Karls University of Tübingen, Tübingen, Germany, 3Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

31P MRSI enables the imaging of important components of the energy and cell membrane metabolism but suffers from low intrinsic sensitivity. In this work, we tested the LORA and CLORA low-rank noise reduction approaches to improve the quality of 3D 31P MRSI data and present first in vivo results for 31P MRSI acquired from the human brain at ultrahigh field strength of 9.4 T.

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